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Salmeterol / Fluticasone Propionate

US Brand Name Advair
Generic Name Salmeterol/ Fluticasone Propionate
Other Brand Name Seroflo, Flutiair-S Puffcaps
Manufacturer Cipla, Sava medica
Packing 30
Form Rotacap
Strength 50 mcg/ 100 mcg, 50 mcg/ 250 mcg, 50 mcg/ 500 mcg
Available online

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Details

Fluticasone

Uses

Fluticasone is used in the treatment of asthma, congestion and sneezing, severe allergic reactions, allergic disorders and other nasal congestion symptoms.

How it Works

Fluticasone helps in preventing the symptoms of nasal congestion from happening. Fluticasone is a steroid which works by reducing the inflammation in the nasal airways. When the inflammation has gone, nasal airways are much less likely to become narrow and cause symptoms such as wheezing or difficulty in breathing.Fluticasone is a corticosteroid medication, Fluticasone relieves nasal symptoms by helping to prevent and reduce inflammation in the nasal passages

Common Side effects

Patients who take Fluticasone may suffer from such side effects;

Nosebleeds,
Nasal irritation,
Sinus pain,
White sores inside the nose,
Back pain,
Electrolyte imbalance,
Increased risk of infection,
Nasal congestion, M
uscle disorders, Vomiting,
Nausea,
Sneezing,
Headache,
Redistribution/accumulation of body fat,
Bone degradation,
Chest tightness,
Sore throat,
Fever,
Increased blood pressure,
Cough, Altered bone growth,
Skin scar,
Stomach upset,
Behavioural changes,
Increased glucose level in blood,
Cataract

Generic Advair, Salmeterol/ Fluticasone Propionate Rotacap

Introduction

Salmeterol is a long standing beta adrenergic bronchodilator, which works by opening up the airway and improving the ability to breathe. The other active component is Fluticasone, which is a corticosteroid that acts by reducing the irritation and swelling of the airway.

Use

This medication is indicated in the treatment and control of symptoms like wheezing or shortness of breath due to recurrent episodes of asthma or continuing lung disease like chronic obstructive pulmonary disease, emphysema, bronchitis, etc.

Fluticasone is a corticosteroid which reduces the mediators of inflammation like cytokines, histamine, etc., and thereby helps control the constriction of the air passage. Salmeterol is known to stimulate the intracellular adenyl cyclase which catalyses the conversion of adenosine tri phosphate to adenosine mono phosphate. Adenosine mono phosphate helps widen the airway and thereby improves breathing.

Dosage and administration

Take this medication exactly as directed by the doctor and follow all the instructions properly. Use of this drug is indicated only if other initial medicines have not proven to be effective.

The recommendation for patients aged 12 years and more is that the usual dose is two inhalations a day (with 12 hours difference between doses).

Rinse the mouth after each use of the rotahaler so as to prevent thrush and oral irritation.

It may take 1 week or longer to notice results from using the medication. Until then, it is advised not to alter the dose or to stop taking the medication without consulting the doctor.

Warning

  • The patient is advised to consult with the doctor about any history of allergies to Fluticasone or Salmeterol before being prescribed this medicine. This drug is known to contain lactose and may pose a problem if you are diabetic or lactose intolerant.
  • Pregnant women and breast feeding mothers are to use this medication only if it has been prescribed by the doctor.
  • This medication is known to make patients drowsy after use therefore, you are advised not to drive or operate any machinery after taking the medicine.
  • Before being prescribed this medication, inform the doctor of your complete medical history, whether you suffer or have suffered from any liver ailments, kidney disease, diabetes, hyperthyroidism, etc. The doctor would then determine if this medication is right for you.
  • It is advised to prime the inhaler before using it for the first time and to re-prime it if you have not used it for 4 weeks.
  • Side effects

  • Nausea
  • Vomiting
  • Dizziness
  • Diarrhea
  • Flatulence
  • Stomach pain
  • Headaches
  • Pneumonia
  • Upper respiratory tract infection
  • Fever with chills and sore throat
  • Itching and rashes