Irbesertan or commonly known as Avapro is an angiotensin II antagonists drug. This medicine has a blood pressure lowering effect, thus, improving the flow of blood. This medication will take full effect when given synergistically with other blood lowering therapy.
Avaproís main component is Irbesertan which is a crystalline powder. This drug with inactive ingredients such as poloxamer 188, lactose, pregelatinized starch, microcrystalline cellulose, silicon dioxide, croscarmellose sodium and magnesium stearate is taken in orally.
This drug medicine is used to treat high blood pressure.
Avapro can be use or taken with full or empty stomach. The starting dose of this drug is 150 mg to be taken once a day then titrating it to 300 mg once a day. If the patient is suffering from neuropathy brought about by type 2 diabetes mellitus the recommended dose is 300 mg once a day. If hypertension is not controlled by using Avapro alone then other therapeutic drug can also be used to achieve synergistic effect. However, for the patient with volume and salt depleted condition initial dose should be lower than the usual. Avapro 75 mg is the recommended initial dose for this type of patient. A very important point to remember is to take the medication as directed by the health care provider. It is okay to take the missed dose of Avapro as long as it is not beyond 12 hour period. Skip the dose if it goes beyond 12 hours, and then go back to your regular therapeutic dose. Commonly reported side effects of taking Avapro are heart burn, swelling in the lower extremity particularly in the ankles, heart burn, tiredness or easy fatigability, diarrhea, and cough.
Pregnant women are advice not to use Avapro. If you have allergic or hypersensitivity reaction to irbesartan you should not use this drug also. It is important to inform your doctor or health care provider if you CHF or congestive heart failure, kidney disease, and liver disease. Alcohol consumption is discouraged too when you are under this therapy. Regular monitoring of blood pressure is also important. Rarely, Avapro can cause kidney diseases.
This medication is not to be used by neonates as this may lead to irreversible damage or even death. When you are pregnant, stop taking Avapro the soonest possible time. Congenital defects have also been reported by pregnant women taking Avapro.
Serious side effects prompting medical attention are dysphagia, dyspnea, fainting, and swelling of the tongue or other parts of the face and head, and hoarseness.
Store or keep Avapro away from light and water. Protect the drug from humid environment. Keep the medicine always out of childrenís reach and strictly follow the usage leaflet and physician or health care providerís advice. Be mindful also of the expiry date and do not forget to discard the medication once it reached its maturity date. Discard the drug properly and safely.