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Losartan Potassium is an angiotensin II receptor antagonist that is prescribed, alone or together with other agents, to help treat hypertension. It is also prescribed to help lower the risk of strokes in individuals suffering from hypertension and left ventricular hypertrophy. It may also be prescribed to help treat certain cases of kidney disease in individuals suffering from type 2 diabetes as well as hypertension.

US Brand Name Cozaar, Cozaar
Generic Name Losartan Potassium
Other Brand NameCovance, Repace, Cosart
Manufacturer FDC, RPG Life Sciences, CADILA, Micro Carsyon, Ranbaxy
Packing 10
Form Tablet
Strength 25 mg, 50 mg, 100 mg
Available online

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Losartan is used in the treatment of hypertension, heart failure, heart attack and diabetic kidney disease.

How it Works

Losartan is known as an angiotensin II receptor antagonist. Losartan works by inhibiting ACE which means it blocks or inhibits a chemical called angiotensin-converting enzyme, which in turn blocks the production of angiotensin II which is the main reason of constricting of the blood vessels, which tends to raise blood pressure.

Common Side effects

Patients who take Losartan may suffer from such side effects;

Orthostatic hypotension,
Renal impairment,
Increased potassium level in blood,


Cozaar belongs to the drug category called angiotension II receptor antagonist. It lowers the blood pressure by keeping the blood vessel narrow, thus, helps in improving blood flow. The generic name for Cozaar is losartan potassium. This medication is manufactured by FDC, RPG Life Sciences, CADILA, Micro Carsyon, and Ranbaxy. Other popular trade names are Covance, Repace, and Cosart.


The main ingredient of this drug is LOSARTAN POTASSIUM. This component is a non peptide molecule. It is off white to white in color. It has a molecular weight of 461.01. The medication is both water soluble and alcohol soluble, however, it is slightly soluble in most organic solvent. This drug can be purchase both online and local drug stores. Inactive components comprising the drug are lactose hydrous, titanium dioxide, starch, magnesium stearate, and microcrystalline cellulose.


This therapy can be use in treating hypertension alone or it can be use coupled with other anti hypertensive drugs for maximum effect. It can be of great help for patient with left ventricular hypertrophy. This can also help for the treatment of neuropathy brought by insulin dependent diabetes mellitus. The maximum health benefit can be obtain when medication is properly used.

Dosage and administration

This drug is taken orally in a full or even in an empty stomach. The initial loading dose of this drug is usually 50 mg once a day. However, dosing can be subsequently adjusted depending on the patientís response to treatment. Diuretic can be added if blood pressure is not controlled with losartan alone. The ideal dose for pediatric patient is 0.7 mg/kg to be given once daily or as prescribed by health care provider. Therapeutic effect can be felt in a matter of three to six weeks. This drug can be supplied via suspension. The ideal dose is 200 mL/2.5 mg/mL suspension. Cozaar in tablet form is tear drop in shape and is light green in color. The usual dose in tablet is 25 mg.


The Cozaar therapy is contraindicated to patient who has hypersensitivity reaction to any of the component of losartan. This drug is also contraindicated to pregnant woman as there were reports that usage of thus drug during pregnancy may lead to fetal defect or worst fetal death. Breastfeeding mothers are also discourage to use this drug as it is reported that component of this medication is secreted in the breast milk.

Important Precautions

It is important to tell your health care provider if you are taking any medications before starting the Cozaar therapy. Studies show that Cozaar interacts with some of the commonly use medication. People who are taking diuretics should be cautious too as Cozaar affects blood pressure. Avoid using potassium supplements while under this therapy.

Side effects

Cozaar is generally well tolerated; however, we all know that every drug has side effects. Reported side effects of Cozaar medication are leg pain, upper respiratory infection, muscle cramps, nasal congestion, and sinusitis. Serious side effects that prompt quick medical attention are palpitation, tachycardia, anorexia or loss of appetite, painful and achy teeth, arthritis, anxiety, sleep walking, difficulty of breathing, and nocturia or frequent urination at night. Prolonged usage of this can also lead to impotence. These are reported and mentioned side effects; however, if you are feeling any adverse effect that you think might prompt medical attention go to your health care provider right away.


Keep the drug away from light and heat. Store the medication is a clean and tight container. The acceptable room temperature for storing the medication is 15 degree Celsius to 30 degree Celsius. Discard the drug properly once expiry date reached.