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Hydrochlorothiazide is a diuretic that is prescribed to help manage high blood pressure as well as edema that is due to various conditions.

US Brand Name Esidrex
Generic Name Hydrochlorothiazide
Other Brand NameAquazide, Hydrazide
Manufacturer CIPLA
Packing 10
Form Tablet
Strength 12.5 mg, 25 mg
Available online

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This medication is a diuretic that is often used to help treat high blood pressure. It prevents the body from absorbing too much salt that acts as a catalyst for fluid retention. It helps the body to flush away extra salt and water.


Hydrochlorothiazide is used to treat fluid retention, also known as edema, in patients suffering from kidney problems, heart failure, or cirrhosis of the liver. This medication is also used to manage high blood pressure. It helps to lower blood pressure thus reducing the risk of strokes or heart attacks.

Dosage and administration

Doctors usually recommended taking this medication once in the morning either on an empty stomach or after a meal. The tablet is to be consumed orally with a glass of water. The dosage is determined by the severity of the condition, as advised by the doctor. When the tablets have been prescribed to be taken twice a day, one dose should be taken in the morning and the other dose is to be taken at least 4 hours before bedtime. Take this medicine exactly as prescribed by the doctor. In case you miss a dose, do not take 2 doses at one time. Just skip the missed dose, take the next scheduled dose, and resume as usual. Your doctor would advise you on the proper use of this medicine.


  • Before being prescribed this medication, inform the doctor of your complete medical history, whether you suffer or have suffered from any liver ailments, kidney disease, diabetes, etc. The doctor would then determine if this medication is right for you.
  • Inform the doctor if have any existing or past allergies to any substances as the medication may have such substances in its composition. In case you experience any allergies or discomfort while using this medication, stop using this medication and consult the doctor immediately.
  • This medication may cause dizziness thus do not perform any activities that require you to remain alert after taking this medication.
  • Do not consume tobacco or alcohol while on this medication as they may reduce its effectiveness.
  • This medication may cause diarrhoea and vomiting thus resulting in the loss of water from the body, which may lead to dehydration. It is advisable that you drink plenty of water while on this medication so as to keep the body properly hydrated.
  • This medication can make your skin sensitive to sunlight thus avoid prolonged exposure to the sun and extreme warm conditions. Apply sunscreen when you are going out and wear proper clothing to avoid extended exposure to the sun.
  • Pregnant women and breast feeding mothers are to use this medication only if it has been prescribed by the doctor.
  • Side effects

    Taking Hydrochlorothiazide may cause side effects. Some common side effects are,

  • Stomach pain.
  • Headaches and dizziness.
  • Severe pain in the eyes and decrease in vision.
  • Dehydration.
  • Heartburn.
  • Diarrhoea.
  • Irregular heartbeat.
  • Muscle cramps.
  • Frequent urination.
  • Dry mouth.
  • Swelling of the face, mouth, or tongue.
  • Trouble breathing.