Levodopa belongs to a class of medication called central nervous system agents. It gets converted to dopamine in the brain. Carbidopa belongs to a class of medication called decarboxylase inhibitors. It works by preventing levodopa from being broken down before it reaches the brain. This allows the effectiveness of a lower dose of levodopa thus causing less nausea and vomiting.
Administration of dopamine alone is ineffective in the treatment of Parkinson's disease because it gets broken down before crossing the blood-brain barrier.
This medication is a combination of Levodopa and Carbidopa. It is used to treat the symptoms of Parkinson's disease and like symptoms that may develop after encephalitis, carbon monoxide poisoning, or manganese poisoning. The symptoms of Parkinson's disease include tremors (shaking), stiffness, and slow movement. This is caused by a lack of dopamine, a naturally occurring substance usually found in the brain.
Dosage and administration
The dosage is based on your medical condition and response to the treatment. Take this medication orally as directed by your doctor, usually 3 to 4 times a day. You can take it with or without food however, taking it with food may help decrease nausea.
It is advised to avoid a high-protein diet since it decreases the amount of levodopa the body takes in, unless instructed otherwise by the doctor. If you are taking any iron supplements, then separate taking them from the hours you take this medication since iron reduces the absorption of the drug in the body.
To reduce the chances of side effects, the doctor may start you off with a low dose of this medication and gradually increase the dose thereafter if deemed necessary. Use this medication regularly as prescribed to get the best results.
This medication comes in a combination of different strengths of carbidopa and levodopa. It is important to have the correct dose for both drugs.