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Combigan Eye Drop (Brimonidine Tartrate/Timolol Maleate) reduces elevated intraocular pressure in individuals suffering from open-angle glaucoma or ocular hypertension who require adjunctive or replacement therapy because of insufficiently controlled intraocular pressure.

US Brand Name Combigan
Generic Name Brimonidine Tartrate+ Timolol Maleate
Other Brand NameCombigan
Form Eyedrop
Strength 0.2% 0.5% 5 ml
Available online

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Brimonidine Tartrate


Brimonidine Tartrate is used in the treatment of open-angle glaucoma or ocular hypertension which is also known as high pressure inside the eye.

How it Works

Brimonidine Tartrate works by reducing the amount of fluid in the eye, which then decreases pressure inside the eye.

Common Side effects

Some of the potential side effects of Brimonidine Tartrate can include the symptoms below;

Blurred or loss of vision,
Burning, dry, or itching eyes,
Discharge or excessive tearing,
Disturbed color perception,
Double vision,
Itching of the eye
Night blindness
Halos around lights,



Timolol is used in the treatment of glaucoma, prevent migraines, hypertension or high blood pressure, Timolol also helps to prevent abnormally fast heart rhythms or also known as arrhythmia.

How it Works

Timolol works by slowing down the activity of the heart by stopping messages sent by some nerves to the heart. Timolol does this by blocking tiny areas which are called beta-adrenergic receptors, where the messages are received by the heart. As a result, the heart beats more slowly and with less force, This then allows the pressure of blood within the blood vessels to be reduced. Timolol also works by lowering the pressure in the eyes, thereby preventing gradual loss of vision.

Common Side effects

Some of the potential side effects of Timolol can include the symptoms below;

Stinging in the eyes,
Blurred vision,
Burning eyes,
Chest pain or discomfort,
Lightheadedness, dizziness, or fainting,
Shortness of breath,
Slow or irregular heartbeat,
Unusual tiredness