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Tiomune, Stavudine/ Lamivudine/ Nevirapine

US Brand Name Tiomune
Generic Name Stavudine/Lamivudine/Nevirapine
Other Brand Name TIOMUNE
Manufacturer CIPLA
Packing 30
Form Tablet
Strength 30+150+200mg, 40+150+200mg

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Details

Introduction

Triomune is a combination drug which is used in the treatment of Human Immunodeficiency Virus (HIV). It consists of 3 drugs, which are Nevirapine, Lamivudine, and Stavudine. Triomune does not cure HIV, but it reduces the growth of HIV in the body thereby promoting immune system function.

Use

The Triomune tablet is used to treat patients with HIV. Usually, a Nevirapine tablet is given first to the patient and depending on the patient’s tolerance, other medications are prescribed. Usually with HIV, there is a decrease in the number of CD4+ cells that are responsible to maintain immunity in the body. These are immune cells which provide resistance from diseases. Triomune inhibits the replication of HIV in the body and also increases CD4+ cells in the body.

Dosage and administration

There are three separate drugs which constitute Triomune. Any person suffering from HIV is first given Nevirapine tablets of 200 mg dosage strength. The patient has to take the tablets twice a day and his tolerance is checked after 2 weeks. If the patient develops any severe side effects or allergies, then the medicine is stopped immediately. If the patient shows tolerance, then other medications can be given to him or her as determined by the doctor. Triomune 30 is available in a combination of 30 mg, 150 mg, and 200 mg for people weighing between 30-60 kg and Triomune 40 is available in a combination of 40 mg, 150 mg, and 200 mg for those weighing more than 60 kg. The medicine must be taken exactly as prescribed by the physician and do not increase the dosage at any time unless recommended by the physician. Consult with your physician immediately if you have any doubts regarding the proper dosage.

Warning

  • Inform the doctor regarding any allergies that you have before being prescribed this medication. If you experience any allergies or discomfort while on this medication, stop taking it and consult the doctor immediately.
  • Inform the doctor about your medical history, if you suffer or have suffered from any liver ailments or kidney disease. Previous surgeries that you have undergone must be informed to the doctor as well.
  • Inform the doctor if you have suffered from liver inflammation or skin rashes while on Nevirapine medication.
  • Avoid intake of the medicine in case of low count of red blood cells and white blood cells in the body.
  • Side effects

    It has several side effects ranging from mild to severe ones that are listed below,

  • Nausea, dizziness, and vomiting.
  • Severe peripheral neuropathy.
  • Liver inflammation and toxicity as this medicine increases lactic acid formation in the body that may lead to liver cirrhosis in extreme cases.
  • Renal failure.
  • Pancreatitis.
  • Difficulty in breathing.
  • Loss of appetite.
  • Weight loss.