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Sinemet

Sinemet (Carbidopa/ Levodopa) may be prescribed to help alleviate the symptoms of Parkinson's disease, post-encephalitic parkinsonism, or symptomatic parkinsonism.

US Brand Name Sinemet
Generic Name Levodopa, Carbidopa
Other Brand NameSinemet
Packing30
Manufacturer MSD
Form Tablet
Strength 250mg / 25mg
Available online
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Details

Levodopa

Uses

Levodopa is used in the treatment of Parkinson's disease or shaking palsy.

How it Works

Levodopa works by improving muscle control. Levodopa is converted to dopamine, a chemical messenger which is needed to control the movement through transmission of signals in the brain. Therefore levodopa allows more normal movements of the body.

Common Side effects

Some of the potential side effects of Levodopa can include the symptoms below;

Nausea,
Vomiting,
Dizziness,
Loss of appetite,
Orthostatic hypotension,
Movement disorder

Carbidopa

Uses

Carbidopa is used in the treatment of Parkinson's disease and to relieve its symptoms

How it Works

Carbidopa is always given along with levodopa. Carbidopa works by preventing levodopa from being broken down into dopamine before it reaches the brain. This means more levodopa gets into the brain to be converted into dopamine.This allows for a lower dose of levodopa to be administered, which causes less nausea and vomiting.

Common Side effects

Some of the potential side effects of Carbidopa can include the symptoms below;

Nausea,
Neuroleptic malignant syndrome,
Panic attacks,
Altered behaviour,
Mood changes,
Fever,
Frequent dreams,
Hallucination,
Increased sweating,
Tachycardia,
Irregular heart rate,
Tremor,
Altered sleep,
Burning sensation of tongue,
Confusion,
Convulsion,
Dizziness,
Drowsiness,
Vomiting,
Worsening of tremor,
Muscle stiffness.