Sorafenib is a drug which belongs to the medication class of tyrosine kinase inhibitors. The drug is used to treat certain cancers like renal cancer, liver cancer, or thyroid cancer.
The drug is indicated for the treatment of hepatocellular carcinoma that cannot be treated with surgery, renal cell carcinoma, or thyroid cancer that has spread to other parts of the body and cannot be treated with radioactive iodine anymore. It functions by acting as a kinase inhibitor. Kinase molecules are thought to be involved in cell signaling, angiogenesis, and apoptosis.
Dosage and administration
Sorafenib is available as tablets of 200 mg concentration. The route of administration is oral. The recommended daily dose of the drug in an adult is 400 mg, two divided doses of 200 mg each that are to be taken as prescribed by the doctor. The drug should be taken with a full glass of water and the tablet should not be chewed or broken. The drug should be taken on an empty stomach, one or two hours before a meal. The accurate drug dose depends on your body weight, age, sex, and your response to the drug. Always follow the doctor’s instructions while taking this medicine. In case you miss a normal dose of the drug, do not take two doses to compensate for the missed dose. Just continue with the usual drug regime on your next dose. Your doctor would advise you on the proper use of this medication.