Tamoxifen belongs to a class of medication known as anti-estrogens. It is used to treat certain forms of breast cancer, which have spread to other parts of the body, both in men and women.
It is used to treat certain breast cancers, which have spread to other parts of the body (metastatic cancer), those which have already been treated with surgery, chemotherapy, or radiotherapy. It is also used to reduce the risk of the development of breast cancer in women who are at high risk due to their family history and age. Its mechanism is that it blocks the effect of a female hormone, estrogen, thereby stopping the growth of cancer cells in the breast, which require estrogen to grow.
Dosage and administration
Tamoxifen is available as tablets of 10 mg or 20 mg concentrations, to be given orally with water. The recommended daily dose of this medicine is 20 mg to 40 mg by oral route. Doses of 20 mg can be given once a day while doses more than 20 mg needs to be divided and given two times a day. Always follow the doctor’s instructions while taking this drug. Do not take more than the prescribed dose. Take the tablet as a whole and do not break or crush it.