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Nifedipine is a calcium channel blocker that is prescribed to help manage hypertension or angina.

US Brand Name Adalat
Generic Name Nifedipine
Other Brand Name Nicardia, Depin 5
Manufacturer Zydus Cadila, J.B. Chemicals
Packing 10
Form Capsule
Strength 5 mg, 10 mg, 20 mg, 30 mg
Available online
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Nifedipine is given for the treatment of hypertension, or to help prevent angina chest pain.

How it Works

Nifedipine is known as a calcium channel blocker. Nifedipine works by causing some of blood vessels to relax and widen. This then lowers blood pressure. Nifedipine also increases the flow of blood to places like hands and feet. Nifedipine reduces the force and the rate of heartbeat, and this helps to prevent angina chest pain. Nifedipine works blocking the amount of calcium that goes into the 'smooth' muscle cells in the walls of blood vessels and in the heart. Calcium is needed for muscles to contract, so reducing the amount of calcium using Nifedipine causes the muscle cells to relax.

Common Side effects

Patients who take Nifedipine may suffer from such side effects;

Ankle swelling,
Abdominal pain


Nifedipine belongs to the group of medicines called calcium channel blockers. It usually dilates your veins and arteries and hence reducing the pressure needed from the heart for blood to flow. This is what makes the drug appropriate for treating hypertension and chest pains. This drug is yellowish in color, water insoluble but can dissolve in ethanol.


Nifedipine is a yellow substance that is in crystalline form not soluble in water. The Nifedipine capsules contain: saccharin sodium, polyethylene glycol, soft gelatin, glycerin as well as oil from peppermint.


Nifedipine should be strictly taken in the prescribed amounts for the prescribed period of time. A deviation from such a prescription could have serious negative repercussions. In addition, you should follow the instructions on the label of the drug. You should take this drug before meals and you should avoid breaking the capsule's cover because this would interfere with the normal absorption of the drug. Some of these tablets have a cover that does not dissolve during digestion and might appear in your stool and this should not alarm you. During the medication of this drug, you should visit your doctor as advised so as to have a check on your blood pressure.

Dosage and administration

Nifedipine should be taken orally in the prescribed doses once a day before meals. To know the amount of this drug that you should take, visit a doctor because this varies with different individuals and can also be varied by the doctor as you continue to take the drug.


While taking this drug you should avoid drinking juice from grapes or eating the grapefruits. If you have to take either of the two, consult your doctor first. While under Nifedipine’s medication never get up too fast if you are lying or sitting position, since this will make you dizzy.

Important Precautions

People that have an allergy to any of the ingredients of Nifedipine should not use the drug. If you suffer from cirrhosis, a kidney disease, a problem of the digestion system or a congestive heart failure then, you should inform your doctor about it. This is necessary so that the doctor can take the appropriate measures in his prescription. If by any chance you are to go to a surgical theatre you are required not to take Nifedipine for a given period of time. The length of this period should be determined by the doctor conducting the surgery and you should inform him of your Nifedipine’s medication. While receiving your prescription from the doctor you should let him know of any other medication you could be taking. Moreover, you should take this drug for the prescribed time even if it is a lifetime.


Among the drugs that interact with Nifedipine we have: antifungal medication, heart rhythm drugs, seizure medication, other blood pressure medications, acarbose, cimetidine, and nefazodone. These drugs will have undesirable results when used with Nifedipine.

Side effects

The side effects associated with this drug are breathing difficulties, facial swelling, hives, swelling of lips and tongue swelling.


Nifedipine should be stored at room temperatures away from the reach of children.