This drug is a proton pump inhibitor. It works mainly by decreasing the production of acid in the stomach. This drug can also be given together with antibiotic to prevent the formation of gastric ulcer caused by H. pylori or helicobacter pylori infection. The generic name for this drug is rabeprazole. This is manufactured by Cadila incorporation. Other popular trade names or brand names of the drug are Rabicip, Rabicer, and Rabasec. This is a delayed release medication.
The active component of this medication is rabeprazole sodium. It is a benzimidazole that promotes the secretion of gastric acid. It is a yellowish white to white in color and is solid in structure. It is a water soluble substance. It is also soluble in ethanol and methanol. However, it is insoluble to ether. The drug is stable in alkaline condition. This is an entic coated that is available to be taken orally. Inactive ingredients of this product are crospovidone, carnauba wax, magnesium stearate, mannitol, titanium dioxide, and coloring agent such as yellow iron dioxide.
The usage of this drug therapy is primarily for GERD or gastro esophageal reflux disease. It usually takes four to six weeks for the gastro esophageal reflux disease to heal, however, and additional eight more weeks can be adds to the treatment. It is also vital as a treatment for duodenal ulcers. In some cases, this drug therapy is use for Zollinger-Ellison syndrome condition. It is also use for other hypersecretory conditions.
Dosage and administration
Take the medication as prescribed by health care provider. Take this drug with water preferably a full glass of water. The medicine should be swallowed. Chewing and crushing of the medication is not recommended. This drug can be taken with full or empty stomach. The recommended dose for gastro esophageal refluc disease is 20 mg of Aciphex to be taken once a day in four weeks to eight weeks period. If using as a maintenance therapy for GERD the suggested dose is 20 mg once a day. For duodenal ulcer, the suggested dosing is 20 mg of Aciphex delayed release once a day ideally after breakfast. For the treatment of hypersecretory condition, the initial loading dose would be 60 mg to be taken orally once a day. This can last up to one year.
The drug therapy is not to be taken by patient with known hypersensitivity reaction to Aciphex and any of its ingredients.
Extra precautionary measures should be given for elderly patient who is under this regimen. This medicine should not be use in pregnant mother as using this drug may cause fetal defects. It is also important to follow health care provider's order in regards to diet and restriction associated with the usage of this drug therapy.
Be watchful of the signs and symptoms of low magnesium level brought about by using this medication. These symptoms are confusion, jittery feeling, and convulsion like symptoms such as tremor, dizziness, and confusion. Common mild side effects are diarrhea, formation or rash that is itchy in nature, headache, nervousness, and sleep disturbance such as insomnia.
Store the medication in a cool and dry place, away from heat, moisture, and direct light. Keep all drugs out of children's reach. Always read and follow drug literature. Discard the drug properly when it is already expired.